恩格列净中间体

Intermediate Name

CAS NO.

Structure

Current Scale

Use

(R)-(2-Chloro-5-iodophenyl) (4-((tetrahydrofuran-3-yl) oxy) phenyl) methanone

 (2--5-碘苯基)[4-[[(3S)-四氢-3-呋喃基]氧基]苯基]甲酮

915095-87-3

 图片12.png

>500Kg

Empagliflozin

 key intermediate

(3S)-3-[4-[(2-Chloro-5-iodophenyl) methyl] phenoxy] tetrahydro-furan

(3S)-3-[4-[(2--5-碘苯基)甲基]苯氧基]四氢呋喃

915095-94-2

 图片13.png

>500 Kg

Empagliflozin

 key intermediate

(R)-3-phenoxytetrahydrofuran

918439-75-5

图片8.png 


Empagliflozin

 key intermediate

(R)-3-phenoxytetrahydrofuran

(3R,4S,5R,6R)-2-(4-chloro-3-(4-(((R)-tetra hydrofuran-3-yl)oxy)benzyl)

phenyl)-3,4,5-tris((trimethylsilyl)oxy)-6-(( (trimethylsilyl)oxy)methyl)

tetrahydro-2H-pyran-2-ol


915095-99-7

图片9.png 


Empagliflozin

 key intermediate


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